Subacute necrotizing encephalopathy in an acidotic child.
نویسندگان
چکیده
Subacute necrotizing encephalopathy was described originally by Leigh (1951). Further case reports reviewed by Ebels, Blokzijl, and Troelstra (1965) have confirmed this condition as a neuropathological entity but ideas concerning its aetiology have remained speculative. Recently Worsley, Brookfield, Elwood, Noble, and Taylor (1965) have reported a case, with confirmation at necropsy, in which there was a persistent lactic acidosis during life. A sibling had died of a similar illness. The authors postulated a disturbance of lactic acid metabolism in this disease. The present report describes a patient with infantile subacute necrotizing encephalopathy in whom a persistent acidosis was a feature of the illness during life.
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Impairment of pyridoxal phosphate dependent metabolic reactions in a child with subacute necrotizing encephalopathy.
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ورودعنوان ژورنال:
- Journal of neurology, neurosurgery, and psychiatry
دوره 30 4 شماره
صفحات -
تاریخ انتشار 1967